Organic/polymer photothermal nanoagents for photoacoustic imaging and photothermal therapy in vivo

Advanced contrast nanoagents for photoacoustic molecular imaging, cytometry, blood test and photothermal theranostics.

Various nanoparticles have raised significant interest over the past decades for their unique physical and optical properties and biological utilities. Here we summarize the vast applications of advanced nanoparticles with a focus on carbon nanotube (CNT)-based or CNT-catalyzed contrast agents for photoacoustic (PA) imaging, cytometry and theranostics applications based on the photothermal (PT)...

Ultrasound and Photoacoustic Imaging to Guide and Monitor Photothermal Therapy

Photothermal and photoacoustic Raman cytometry in vitro and in vivo

An integrated Raman-based cytometry was developed with photothermal (PT) and photoacoustic (PA) detection of Raman-induced thermal and acoustic signals in biological samples with Raman-active vibrational modes. The two-frequency, spatially and temporally overlapping pump-Stokes excitation in counterpropagating geometry was provided by a nanosecond tunable (420-2300 nm) optical parametric oscill...

Multifunctional GQDs-Coated Fe/Bi Nanohybrids for CT/MR Dual Imaging and in vitro Photothermal Therapy

Introduction: The multipurpose nanocomposites have gained growing biomedical attention as promising nanotheranostics to improve The effectiveness of cancer treatment, which concurrently combine advantages of the therapeutic and diagnostic techniques into one nanosystem. The “all-in on” probes not only help to ablate cancerous tumors, but also allow to optimize and monitoring of...

Optical fiber photoacoustic-photothermal probe.

We describe the operation of an all-optical probe that provides an alternative means of implementing photoacoustic and photothermal investigative techniques, particularly those used in biomedical applications. The probe is based on a transparent, acoustically and thermally sensitive Fabry-Perot polymer film sensor mounted at the end of an optical fiber. We demonstrate the ability of the system ...